Figure 2.

Representative histopathological findings in the colon [haematoxylin & eosin (H&E) staining]. Representative histopathological changes of the colon [H&E stain, magnification 100× (first row) and 400× (second row)]. Distension of mucosa and submucosa by infiltration of inflammatory cells, fibrosis, loss and proliferation of crypts in dextran sodium sulphate (DSS) group compared with a regular colon without pathological changes in NC, Em and Em+DSS groups. Higher magnification reveals ulceration of the mucosal epithelium with infiltration of neutrophils (asterisk) and lymphocytes in the depth of the lamina propria mucosae (arrow). [Colour figure can be viewed at http://wileyonlinelibrary.com]