Table 1.
Potential biomarkers in samples and corresponding metabolic pathways.
| Number | RT | Mass | Biomarker identification |
KEGG | Change trend | Pathway | |
|---|---|---|---|---|---|---|---|
| Trenda | Trendb | ||||||
| (1) | 15.64 | 329.3297 | Dihydroceramide | C12126 | ↑ | ↓ | Sphingolipid metabolism |
| (2) | 28.35 | 563.441 | Ceramide | C00195 | ↑ | ↓ | Sphingolipid metabolism |
| (3) | 29.94 | 701.2065 | PC(16:1(9Z)/14:1(9Z)) | C00416 | ↓ | ↑ | Glycerophospholipid metabolism |
| (4) | 18.39 | 569.3487 | LysoPC (22:5) | C04230 | ↑ | ↓ | Glycerophospholipid metabolism |
| (5) | 26.68 | 296.2828 | Thromboxane A2 | C02198 | ↑ | ↓ | Arachidonic acid metabolism |
| (6) | 26.68 | 255.2564 | Nicotinamide riboside | C03150 | ↓ | ↑ | Nicotinate and nicotinamide metabolism |
| (7) | 0.68 | 220.1793 | 5-HTP | C00643 | ↑ | ↓ | Tryptophan metabolism |
Note. aTrends of model group compared with normal group of metabolites. p < 0.05 compared to normal group. bTrends of Uncaria group compared with model group of metabolites. p < 0.05 compared to model group. ↑: upregulated. ↓: downregulated.