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Confocal photomicrographs of labeled layer V pyramidal neurons in the medial prefrontal cortex. The left figure shows the low numbers of dendritic spines present in the dendrites of layer V pyramidal neurons after 21 days of chronic uncontrollable stress (CUS). The right figure illustrates the reversal by a single dose of ketamine 1 day later. Red arrows highlight dendritic spines present after ketamine
