Fig. 4.

Probability of the presence of P. falciparum and P. vivax genotypes. a–c Infection dynamics in PNG participant 1. d–f Infection dynamics in PNG participant 2. g–i Infection dynamics in Thai participant 1. For each genotype within each individual, the colours denote whether that genotype is predicted to be present at a given time arose from that individual’s first, second or third infection. Each P. falciparum infection comes from a separate mosquito bite. Each P. vivax infection comes from either a new mosquito bite or a relapse. The bottom row depicts the probability that a new infection with a P. vivax genotype is due to re-infection from mosquito or relapse. The grey region denotes the period of prophylaxis when participants were treated with AL and chloroquine, and either primaquine or a placebo. During the period of follow-up AL treatment was administered by the investigators to some of the Papua New Guinean participants