. Author manuscript; available in PMC: 2018 Apr 18.

Published in final edited form as: J Proteome Res. 2016 Jun 24;15(8):2787–2801. doi: 10.1021/acs.jproteome.6b00366

Table 1.

Overview of the novel modifications identified in P. falciparum

PTM	H2A	H2A.Z	H2B	H2B.Z	H3	H3.3	CenH3	H4
Kac			K35^c				K23^nc	K67^a, ^nc
			K64^nc				K26^nc
							K60^a, ^nc

STac	T101^a		S24	T30^nc		T11		S47^a
			S28^a	S54		S86
			S50^nc		T107
			T61^nc

me1	K75							K91^a

me2			K64		K115			K67

me3			K35		K115
			K49
			K64

fo	K20	R115	R25	R29	K14		R108	R45
	K41^nc		K49	K53	K27
	R42		K64	R95	K36	K36
					R42^b	R42^b
					R53	K53
					R72	R72
					R83
					R116^b	R116^b

oh	P48	Y77	Y32	K53	Y54			D68
	Y50	H138	K35	D64	K79			Y72
	Y57	K139	K38	D67^nc		K53		K77
	K118		P42			Y99		D85
			K49		D106	D106
			D60		H113	H113
			K64		K115	K115
			P95		P121^b	P121^b
			K100

phs			S56^a		Y78^nc

cr			K49^a		K115^a	K115

Detection of the underlined residues/PTMs was confirmed independently by MRM (SI-6.2).

Modifications carried by peptides indistinguishable between the H3/H3.3 isoforms.

^nc

Residues/PTMs non-conserved in non-apicomplexan species (SI-3.2).

Residues in bold were mapped to the human nucleosome core particle obtained by X-RAY diffraction with a resolution of 2.40 Å (5AV5.pdb)⁷⁵. The full-sized figures are provided in SI-3.3.B.