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The graph shows nodule VRR for consecutively treated nodules at 3 and 12 months since introduction of the RFA method. Analysis of variance was significant for VRR at three months (p = 0.01) but not at 12 months (p = 0.08). The trend over time suggests a VRR difference of approximately 10% and a learning curve for monopolar RFA that reached a plateau quite early.
