Table 1.
Demographics, clinical characteristics and TNF-α level in POAG cases and controls
| Variables | POAG (n = 51) | Controls (n = 88) | p-value |
|---|---|---|---|
| Age, mean (SD) (years) | 59.0 (13.2) | 57.1 (12.1) | 0.409a |
| Gender (M/F) | 29/22 | 53/35 | 0.697b |
| Diabetes mellitus, n (%) | 22 (43.1) | 28 (31.8) | 0.287b |
| Hypertension, n (%) | 20 (39.2) | 28 (31.8) | 0.377b |
| Hypercholesterolemia, n (%) | 2 (3.9) | 3 (3.4) | 0.751b |
| Coronary artery disease, n (%) | 1 (1.9) | 2 (3.4) | 0.628b |
| Smoking, n (%) | 2 (3.9) | 4 (4.5) | 0.795b |
| TNF-α, mean (SD) (pg/mL) | 1.88 (2.17) | 0.93 (1.49) | 0.003a |
Notes:
a
Independent sample t-test.
b
Pearson’s chi-square test.
Abbreviations: F, female; M, male; POAG, primary open-angle glaucoma; TNF-α, tumor necrosis factor alpha.