Table 2.

Diagnostic Accuracy Evaluation of Sputum Auramine Smear and Xpert MTB/RIF Assay by the Reference Standard of Positive Culture From Any Site (n = 255) Among 484 Seriously Ill Human Immunodeficiency Virus–Infected Participants Presenting With a Cough of Any Duration and ≥1 World Health Organization Danger Sign

Parameter	Xpert MTB/RIF	Auramine Smear
Sensitivity, %	86.3 (81.5–90.3)	57.0 (50.7–63.2)
Specificity, %	96.1 (92.6–98.2)	98.7 (96.2–99.7)
Positive predictive value, %	96.1 (92.7–98.2)	98.0 (94.2–99.6)
Negative predictive value, %	86.2 (81.4–90.2)	67.2 (61.9–72.2)
Positive likelihood ratio	21.9 (11.5–41.6)	43.3 (14.0–134.0)
Negative likelihood ratio	0.14 (.11–.19)	0.44 (.38–.50)

Values in parentheses indicate the 95% confidence interval.