Table 1.

Cardiac arrhythmias in wild-type and mutant mice

Mouse model	N	% VT	% Sustained VT	VT Duration (s)	VT mean ± S.E.M. (s)	% Bigemini	Heart rate
Wild type	16	0	0	–	–	0	430±10
Congenital deletion	25	48	24	7–1814	456±174	44	381±6
Conditional deletion	24	33	17	8–890	172±113	12	405±25
Conditional CCS deletion	17	0	0	–	–	0	407±14
Conditional rescue	15	0	0	–	–	0	468±11
Conditional CCS rescue	15	0	0	–	–	0	488±10

Data were collected from anesthetized mice at 6 and at 8 months (Fig. 1C). For calculating %VT, % Sustained VT and % bigemini, a single event in either reading was sufficient. VT durations for each mouse were calculated by summing the durations from each reading. The range of VT durations are reported in this table and described in detail in Fig. 3D. Heart rate (mean ± S.E.M.) for each mouse is the average of basal (pre-stress) heart rates from both readings.