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. 2017 Nov 27;34(8):1353–1362. doi: 10.1093/bioinformatics/btx766

Fig. 1.

Fig. 1.

Data modeling approach, employing BEMKL method, applied on NCI60 genomics (point mutations and CNV), molecular (gene and miRNA expression) and proteomics (MS and RPPA) profiles across 58 pan-cancer cell lines to predict drug response of selected drugs. The BEMKL method learns the multi-view kernel weights to form a joint kernelized representation of the data which is used with the multi-task drug weights to model the response profile across the cell lines to each individual drug (the outcome matrix at the right)