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. 2017 Dec 8;23(3):316–323. doi: 10.1634/theoncologist.2017-0544

Table 1. Clinical features of patients with germ cell tumors or sex cord stromal tumors treated with brentuximab vedotin.

image

H‐score (range 0–300) was calculated as the product of the intensity of CD30 staining (0–3) multiplied by the percentage of positively staining cells (0–100).

a

This patient achieved a partial response at a single time point only.

b

Metastatic disease displayed pure EC histology.

Abbreviations: AFP, alpha‐fetoprotein; BL, baseline value; C, cycle; D, day; EC, embryonal carcinoma; GCT, germ cell tumor; H‐score, histo score; HCG, human chorionic gonadotropin; min, minimum on‐study value; N, normal or not performed.