Fig. 3.
Hepatic G6Pase-α restoration normalizes glycolysis and HMS. L-G6pc−/− mice were treated with 1×1012 vp/kg of rAAV-G6PC at 4 WP and analyzed at 12 WP. (A) Western-blot analysis of c-Myc, GPI, aldolase B, and β-actin in liver lysates and quantification by densitometry (n = 4). (B) Hepatic levels of NADPH (n = 4) and GSH (n = 4). Data represent the mean ± SEM. *P < 0.05, **P < 0.005.