FIG. 10.

Potassium and zinc levels fall after CORM-401 addition. E. coli cells were grown to the exponential phase in Evans medium supplemented with 20 mM glucose. Samples were taken immediately before (t = 0) and at time intervals after 67 μM CORM-401 addition (final concentration). Cell pellets were analyzed using ICP-MS. (A) Intracellular potassium and iron levels; potassium falls significantly between t = 0 and t = 80 (p = 0.03). (B) Zinc and copper levels; zinc levels fall between t = 0 and t = 80. n = 3 ± SEM. ICP-MS, inductively coupled plasma mass spectrometry.