Fig 3. The effect of 48 hours of TH on the urine metabolome of HIE newborns.

Score scatter plots of (A) PCA model of urine samples collected from HIE babies at birth (HIE day 1, empty circles) and during the TH treatment at 48 hours (HIE day 2, red squares). The label NS indicates the non-surviving babies, and (B) corresponding PCA model after removal of the samples belonging to non-surviving newborns.