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Representative NIR optical images of mice with femur implants challenged with PMMA particles on left femur and PBS on the contralateral side. Images were obtained 0.5, 24, 48, 72, 96, 120, 144 and 168 hr after one intravenous injection of P-Dex (MW ~ 35 kDa, with different Dex content) at designed time points. Pseudo color-coded signal intensity reflects the level of polymers within the mice. The signal intensity was normalized using the same intensity scale for each image.
