Fig. 5.

Intraprostatic CaP heterogeneity in performance of genomic prognosticator and AR activity scores. (A) For each CaP focus from which RNA sequencing data were generated, the gene expression signatures measured in the Oncotype DX, Prolaris, and Decipher assays were quantified as corresponding scores. (B) Using gene expression profiles from the same CaP foci, expression of 20 AR-dependent genes was quantified as an AR activity score. The gene expression signatures used to generate these scores are listed in Supplementary Table 16. AR = androgen receptor.