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Stain Matrix Initialization
| Input: Blue channel of RGB image |
| Output: Stain matrix M3×2 |
| Step 1: Compute LoG response of the input |
| Step 2: Compute local peaks of the LoG response |
| Step 3: Compute the density distribution of the peaks |
| Step 4: Select a conservative representative subset of minimum (e.g., negative values) and maximum (e.g., positive) peaks from the density distribution |
| Step 5: Average RGB values of minimum and maximum peaks of Step 4 to set the initial stain matrix |
