Table 2.
Baseline and post-treatment endoscopic and histologic findings
| All (n = 55) | Nonresponders (n = 28) | Responders (n = 27) | p* | |
|---|---|---|---|---|
| Endoscopic findings, n (%) | ||||
| Baseline | ||||
| Rings | 43 (78) | 24 (86) | 19 (70) | 0.21 |
| Furrows | 36 (65) | 21 (75) | 15 (56) | 0.13 |
| Stricture | 41 (74) | 18 (64) | 23 (85) | 0.12 |
| Narrowing | 24 (44) | 16 (57) | 8 (30) | 0.06 |
| Crepe-paper mucosa | 2 (4) | 2 (7) | 0 (0) | 0.49 |
| White plaques | 20 (36) | 8 (29) | 12 (44) | 0.22 |
| Decreased vascularity | 20 (36) | 11 (39) | 9 (33) | 0.65 |
| Post-treatment | ||||
| Rings | 37 (67) | 24 (86) | 13 (48) | 0.003 |
| Furrows | 31 (56) | 23 (82) | 8 (30) | <0.001 |
| Stricture | 22 (40) | 11 (39) | 11 (41) | 0.91 |
| Narrowing | 17 (31) | 10 (36) | 7 (26) | 0.43 |
| Crepe-paper mucosa | 0 (0) | 0 (0) | 0 (0) | N/A |
| White plaques | 15 (27) | 7 (25) | 8 (30) | 0.70 |
| Decreased vascularity | 13 (24) | 8 (29) | 5 (19) | 0.38 |
| Peak eosinophil counts (mean eos/HPF ± SD) | ||||
| Baseline | 82.5 ± 76.6 | 85.8 ± 66.9 | 79.1 ± 86.7 | 0.75 |
| Post-treatment | 34.7 ± 37.0 | 61.1 ± 30.2 | 2.5 ± 4.5 | <0.001 |
| Esophageal diameter† (mean mm ± SD) | ||||
| Before dilation | 11.2 ± 3.4 | 10.8 ± 3.5 | 11.7 ± 3.3 | 0.35 |
| After dilation | 16.2 ± 2.5 | 15.8 ± 2.7 | 16.6 ± 2.1 | 0.19 |
| Increase in esophageal diameter after dilation (mean mm ± SD) | 4.9 ± 2.7 | 5.0 ± 2.8 | 4.9 ± 2.7 | 0.92 |
| Number of total dilations needed, after treatment (mean ± SD) | ||||
| Unadjusted | 3.0 ± 4.3 | 4.1 ± 4.8 | 1.9 ± 3.4 | 0.05 |
| Adjusted‡ | – | 4.6 ± 4.6 | 1.6 ± 4.6 | 0.03 |
*Means compared with t-test and proportions compared with chi-square.
†Diameter reflects the initial dilator size used before dilation, and the last dilation size used for the final dilation on record.
‡Adjustment for age, gender, presence of a focal stricture, initial esophageal diameter, and presence of dysphagia using multiple linear regression.