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. Author manuscript; available in PMC: 2019 Apr 18.
Published in final edited form as: ACS Chem Neurosci. 2018 Jan 8;9(4):838–848. doi: 10.1021/acschemneuro.7b00297

Figure 1.

Figure 1

Histone modifications are altered in the context of yeast overexpressing TDP-43, FUS, and α-synuclein (α-Syn). Shown are p values for the ratios of histone H2A, H2B, H3, and H4 PTM abundances in yeast strains expressing TDP-43, FUS, and α-Syn relative to control cells. The scale is based on p values derived from statistical analysis of Western blotting experiments. The p values were calculated using a two-tailed t test with Welch’s modification. Green indicates more statistically significant decreased modification levels, while red indicates more statistically significant increased modification levels.