Figure 3. IL-15C Treatment Has Little Effect on T Cell Numbers in the Spleen and Brain.
The spleens and brains of untreated or prophylactically IL-15C-treated PbA-infected mice (n = 9/group) were harvested on day 6 pi for CD8+ T cell analysis. Gating strategy to identify GAP50-specific CD8+ T cells in the spleen (A) and brain (D). The frequency (B and E) and number (C and F) of total and GAP50-specific CD8+ T cells in the spleen (B and C) and brain (E and F) were quantified. Data are combined from three independent experiments and presented as the mean ± SEM (B, C, E, F). *p < 0.05, **p < 0.01, **p < 0.01, ****p < 0.0001 as determined by two-way Student’s t test.