Table 4.

Association between number of chronic physical conditions and other modifiable factors with mild cognitive impairment estimated by multivariable logistic regression

Characteristic	Category	Overall (Age ≥50 years)		Age 50–64 years		Age ≥65 years
		OR	95%CI	OR	95%CI	OR	95%CI
No. of chronic conditions	0	1.00		1.00		1.00
	1	1.21*	[1.03,1.42]	1.23*	[1.02,1.48]	1.14	[0.83,1.55]
	2	1.37***	[1.14,1.63]	1.40**	[1.14,1.73]	1.33	[0.91,1.95]
	3	1.75***	[1.43,2.14]	1.91***	[1.45,2.51]	1.66**	[1.21,2.27]
	≥4	2.07***	[1.70,2.52]	2.41***	[1.76,3.29]	1.85***	[1.36,2.50]
Smoking	Never	1.00		1.00		1.00
	Current	1.20*	[1.01,1.43]	1.23*	[1.00,1.50]	1.24	[0.91,1.69]
	Former	1.20	[0.97,1.50]	1.16	[0.86,1.58]	1.22	[0.88,1.69]
Alcohol consumption	Never	1.00		1.00		1.00
	Non-heavy	0.97	[0.82,1.15]	1.03	[0.85,1.26]	0.95	[0.73,1.23]
	Heavy	1.22	[0.93,1.61]	1.18	[0.81,1.72]	1.31	[0.86,2.00]
Low physical activity	No	1.00		1.00		1.00
	Yes	1.24**	[1.08,1.43]	0.83	[0.69,1.00]	1.72***	[1.40,2.11]
BMI (kg/m2)	<18.5	1.21	[1.00,1.47]	1.44**	[1.11,1.87]	0.95	[0.67,1.34]
	18.5–24.9	1.00		1.00		1.00
	25.0–29.9	0.93	[0.81,1.06]	1.07	[0.90,1.27]	0.78*	[0.64,0.95]
	≥30.0	1.30*	[1.02,1.65]	1.54**	[1.12,2.11]	1.06	[0.76,1.49]
Depression	No	1.00		1.00		1.00
	Yes	0.93	[0.69,1.24]	0.87	[0.61,1.25]	0.90	[0.57,1.44]

Abbreviation: OR odds ratio; CI confidence interval; BMI Body mass index

The model is mutually adjusted for all variables in the Table, sociodemographic variables (age, sex, education, wealth), and country.

^*p<0.05,

^**p<0.01,

^***p<0.001