Table 5.
Relationship between transfusion of RBC, plasma, or platelets between days 1–7 to outcome of ALF at day 21.
| Treatment During Inpatient (Day 1–7) | Outcome at Day 21 | ||||
|---|---|---|---|---|---|
| Spontaneous Survivors (N=713) N (%) |
Non-Spontaneous Survivors (NSS) | P* | |||
| All NSS (N=944) N (%) |
Liver Transplantation (N=430) N (%) |
Death (N=599) N (%) |
|||
| Vitamin K | 152(20%) | 143(15%) | 54(13%) | 92(15%) | 0.006 |
| rVIIa | 9(1.2%) | 28(2.8%) | 16(4%) | 13(2%) | 0.022 |
| RBC Transfusion | 207(27%) | 444(45%) | 197(46%) | 278(46%) | < 0.001 |
| Plasma Transfusion | 302(39%) | 692(70%) | 312(73%) | 415(69%) | < 0.001 |
| Platelet Transfusion | 122(16%) | 313(32%) | 141(33%) | 192(32%) | < 0.001 |
p-value compares probability of receiving the indicated treatment between spontaneous survivors and subjects who either received a liver transplant and/or died.