. Author manuscript; available in PMC: 2019 Jun 1.

Published in final edited form as: Pediatr Obes. 2017 Oct 10;13(6):374–380. doi: 10.1111/ijpo.12249

Table 2. Association of cluster groups with outcomes.

Variable	Median (IQR)		Median Split	Number (Percentage) of Patients		P-value	OR (95% CI)
Variable	Group 1^*	Group 2 ^ɨ	Median Split	Group 1^*	Group 2 ^ɨ	P-value	OR (95% CI)
	N=8	N=11
Spexin (ng/mL)	0.62 (0.43, 0.95)	0.31 (0.27, 0.40)	LEM	1 (11.1%)	8 (88.9%)	0.009	Ref
Spexin (ng/mL)	0.62 (0.43, 0.95)	0.31 (0.27, 0.40)	GEM	7 (70.0%)	3 (30.0%)	0.009	0.05 (.004, 0.64)
Leptin (ng/mL)	19.7 (18.2, 32.7)	58.2 (48.9,80.7)	LEM	8 (88.9%)	1 (11.1%)	<0.001	n/a
Leptin (ng/mL)	19.7 (18.2, 32.7)	58.2 (48.9,80.7)	GEM	0 (0.0%)	10 (100.0%)	<0.001	n/a
Insulin mcIU/mL	20 (14.3, 36.7)	35.6 (24.4, 42.2)	LEM	5 (55.6%)	4 (44.4%)	0.260	Ref
Insulin mcIU/mL	20 (14.3, 36.7)	35.6 (24.4, 42.2)	GEM	3 (30.0%)	7 (70.0%)	0.260	2.9 (0.4, 19.2)
Hs-CRP mg/L	<3 mg/L	≥ 3 mg/L	LEM	7 (63.6%)	4 (36.4%)	0.026	Ref
Hs-CRP mg/L	<3 mg/L	≥ 3 mg/L	GEM	1 (12.5%)	7 (87.5%)	0.026	12.3 (1, 139)

Note: LEM(Lower median split) contains subjects with a value less than median; GEM(Upper median split) contains the subjects with a value greater than or equal to median; OR = odds ratio; CI= confidence interval; Ref= referent; OR is not available (n/a) as frequency of a cell is 0.

(high level of spexin and low level of leptin)

^ɨ

(low level of spexin and high level of leptin)

Group 1 (min, max): Spexin (0.28, 1.26); Leptin (17.74, 36.47); Insulin (12.9, 94.9)

Group 2 (min, max): Spexin (0.20, 0.49); Leptin (40.51, 93.51); Insulin (20.1, 45.1)