Skip to main content
. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Bioorg Med Chem Lett. 2017 Oct 18;28(16):2794–2796. doi: 10.1016/j.bmcl.2017.10.034

Figure 3.

Figure 3

2H-4-Ru modified the sequence of r(CUG)250 in a Drosophila model of DM1. RT-qPCR analysis of DsRed-r(CUG)250 and the control genes, 18S and rp49, after anti–8-oxoG immunoprecipitation of RNA from fly larvae treated with 2H-4-Ru. Greater enrichment of DsRed with irradiation suggests that DsRed-r(CUG)250 is selectively modified. Pull-down of 18S and rp49 may suggest a lack of exquisite selectivity of the antibody.