Table 1. Comparison between patients with low vs. high FEV1/FVC ratios.
| Variables | All (n=74) | FEV1/FVC ratio ≥0.74 (n=24) | FEV1/FVC ratio <0.74 (n=50) | P |
|---|---|---|---|---|
| Age, years | 0.68 | |||
| ≤65 | 36 (49%) | 13 (54%) | 23 (46%) | |
| >65 | 38 (51%) | 11 (46%) | 27 (54%) | |
| Sex | 0.02 | |||
| Female | 10 (13%) | 7 (29%) | 3 (6%) | |
| Male | 64 (87%) | 17 (71%) | 47 (94%) | |
| ECOG PS score | 0.37 | |||
| 0 | 20 (27%) | 5 (21%) | 15 (30%) | |
| 1 | 44 (59%) | 17 (71%) | 27 (54%) | |
| 2 | 10 (14%) | 2 (8%) | 8 (16%) | |
| Smoking history | 0.23 | |||
| No | 9 (12%) | 5 (21%) | 4 (8%) | |
| Yes | 65 (88%) | 19 (79%) | 46 (92%) | |
| Chemotherapy cycle | 0.16 | |||
| <4 | 6 (8%) | 4 (17%) | 2 (8%) | |
| ≥4 | 68 (92%) | 20 (83%) | 48 (92%) | |
| Sequential CRT | 0.40 | |||
| No | 61 (82%) | 18 (75%) | 43 (86%) | |
| Yes | 13 (18%) | 6 (25%) | 7 (14%) | |
| RT fractionation | 0.28 | |||
| Once daily | 12 (16%) | 6 (25%) | 6 (12%) | |
| Twice daily | 62 (84%) | 18 (75%) | 44 (88%) | |
| Complete response | 1.00 | |||
| No | 32 (43%) | 10 (42%) | 22 (44%) | |
| Yes | 42 (57%) | 14 (58%) | 28 (56%) | |
| PCI | 1.00 | |||
| No | 40 (54%) | 13 (54%) | 27 (54%) | |
| Yes | 34 (46%) | 11 (46%) | 23 (46%) |
FEV1, pretreatment forced expiratory volume in 1 second; FVC, forced vital capacity; ECOG PS, Eastern Cooperative Oncology Group performance status; CRT, chemoradiotherapy; RT, radiotherapy; PCI, prophylactic cranial irradiation