Table 1. Patients clinic-pathologic characteristics.
Variables | All patients | Patients with ERR | Patients without ERR |
---|---|---|---|
Patients enrolled, n (%) | 40 (100.0) | 30 (75.0) | 10 (25.0) |
Gender, n (%) | |||
Male | 19 (47.5) | 14 (46.7) | 5 (50.0) |
Female | 21 (52.5) | 16 (53.3) | 5 (50.0) |
Age, years | |||
Median [range] | 62 [40–85] | 61 [40–85] | 69 [41–84] |
Race, n (%) | |||
European | 38 (95.0) | 28 (93.3) | 10 (100.0) |
Others | 2 (5.0) | 2 (6.7) | 0 |
Smoking, n (%) | |||
Yes | 9 (22.5) | 6 (20.0) | 3 (30.0) |
No | 30 (75.0) | 23 (76.7) | 7 (70.0) |
Unknown | 1 (2.5) | 1 (3.3) | 0 |
Packs, years | |||
Median [range] | 0 [0–185] | 0 [0–185] | 0 [0–102] |
Performance status, n (%) | |||
0 | 14 (35.0) | 10 (33.3) | 4 (40.0) |
1 | 22 (55.0) | 16 (53.3) | 6 (60.0) |
2 | 4 (10.0) | 4 (10.3) | 0 |
Pathology, n (%) | |||
Adenocarcinoma | 39 (97.5) | 29 (96.7) | 10 (100.0) |
Others | 1 (2.5) | 1 (3.3) | 0 |
Stage, n (%) | |||
IIIB | 2 (5.0) | 2 (6.7) | 0 |
IV | 38 (95.0) | 28 (93.3) | 10 (100.0) |
Number of prior CT, n (%) | |||
0 | 25 (62.5) | 21 (70.0) | 4 (40.0) |
1 | 10 (25.0) | 7 (23.3) | 3 (30.0) |
2 | 3 (7.5) | 1 (3.3) | 2 (20.0) |
>2 | 2 (5.0) | 1 (3.3) | 1 (10.0) |
TKI, n (%) | |||
Erlotinib | 30 (75.0) | 23 (76.7) | 7 (70.0) |
Gefitinib | 8 (20.0) | 6 (20.0) | 2 (20.0) |
Afatinib | 2 (5.0) | 1 (3.3) | 1 (10.0) |
ERR, early radiological response; CT, computed tomography; TKI, tyrosine kinase inhibitor.