Figure 3.

Cilia impairment. CP110 (red) were double stained with cilia (βIV-tubulin, green) in non-hyperplastic and hyperplastic epithelium in bronchi and bronchioles respectively (A, ×400 amplifications; scale bar =20 µm). Statistical analysis was performed in non-hyperplastic and hyperplastic epithelium in bronchi and bronchioles in cilia length in paraffin section (B, Mann-Whitney two-tailed U test; Median values with 25th and 75th percentiles are indicated by horizontal red lines). CP110 were evaluated by TFI (C, Mann-Whitney two-tailed U test; Median values with 25th and 75th percentiles). The correlations between TFI of CP110 and cilia length (one-to-one) were analyzed respectively (D and E).