Table 1.
A summary of the effect of different GDNF signalling mechanisms on explant branching
| Figures | GDNF-stimulated cell division | Chemotaxis | Anisotropic cell division (ACD) | Branching |
|---|---|---|---|---|
| 4, 5a | − | − | − | − |
| 4, 5b | + | − | − | + |
| 4, 5c | − | + | − | − |
| 4, 5d | + | + | − | + |
| 4, 5e | − | − | + | − |
| 4, 5f | + | − | + | ++ |
| 4, 5g | − | + | + | − |
| 4, 5h | + | + | + | ++ |
Each row of the table corresponds to specific panels of Figs. 4 and 5, with corresponding parameter sets indicated in Table S1. In the middle three columns “−” indicates that the mechanism is inactive, “+” indicates that it is active. In the right-hand column “−” indicates no significant branching, “+” indicates modest branching and “++” indicates that branching that is consistent with experimental data