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. 2018 Apr 12;9:451. doi: 10.3389/fimmu.2018.00451

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Copyright © 2018 Tong, Lönnblom, Yau, Nandakumar, Liang, Ge, Viljanen, Li, Bãlan, Klareskog, Chagin, Gjertsson, Kihlberg, Zhao and Holmdahl.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum antibody response to native CII and CXI in C^IIIA and C^XIIA mice. Serum antibody response to native CII (left panel) and CXI (right panel) protein on day 21 or day 70 were measured in C^IIIA and C^XIIA DBA/1J mice using enzyme-linked immunosorbent assays (ELISA). Naïve mice sera samples were served as negative control. Mann–Whitney U-test was used for group comparison.