Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 18;9:1532. doi: 10.1038/s41467-018-03915-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — Cross-vaccination of 4T1 and EMT6 tumor xenografts by autologous or allogeneic cancer vaccines. a Cross-vaccination experimental design. b, c Distant tumor growth curves and tumor-free percentages of the distant EMT6 tumor-bearing BALB/c mice model. The mean tumor volumes were analysed using one-way ANOVA. ***p < 0.01. Data represent mean ± s.d. (n = 6). d, e Distant tumor growth curves and tumor-free percentages of the distant 4T1 tumor-bearing BALB/c mice. The mean tumor volumes were analysed using one-way ANOVA. ***p < 0.01. Data represent mean ± s.d. (n = 6). f Representative flow cytometry plots showing the proportions of tumor-infiltrating CTLs in distant EMT6 or 4T1 tumors. Data represent mean ± s.d. (n = 3). g Tumor mass-normalized intratumoral infiltration of CD8⁺ T cells in distant EMT6 or 4T1 tumors. h, i Vaccination-induced secretion of tumor specific IFN-γ by the h peripheral blood mononuclear lymphocytes (PMBCs), and i the spleen lymphocytes, respectively. g–i Unpaired student’s t-test (two-tailed) was used for the comparison between two groups. ***p < 0.01. Data represent mean ± s.d. (n = 3)