Table 2.
Parameters of model of open channel probabilities determined by acidic and alkalic sensing domains at different levels of [Mg2+]i.
| [Mg2+]i, mM | Aacid | pH1/2, acid | Aalk | pH1/2, alk | gmax, nS | |
|---|---|---|---|---|---|---|
| Cx36-EGFP | 0.01 | 0.77 | 6.70 | 4.23 | 7.90 | 2.42 |
| 1 | 1.42 | 5.75 | 2.34 | 7.59 | 1.80 | |
| 5 | 0.00 | 5.39 | 3.00 | 7.53 | 1.39 | |
| Cx36*E8Q-EGFP | 0.01 | 1.65 | 6.16 | 9.05 | 7.84 | 1.31 |
| 1 | 1.43 | 6.77 | 2.83 | 7.70 | 1.91 | |
| 5 | 0.32 | 5.03 | 3.64 | 7.74 | 0.55 | |
| Cx36*E12Q-EGFP | 0.01 | 1.77 | 7.15 | 7.71 | 7.81 | 2.13 |
| 1 | 3.53 | 6.04 | 5.15 | 7.75 | 1.08 | |
| 5 | 0.51 | 6.49 | 3.59 | 7.71 | 0.80 | |
| Cx36*E8Q-E12Q-EGFP | 0.01 | 0.97 | 7.89 | 3.44 | 7.71 | 4.22 |
| 1 | 1.12 | 7.88 | 4.16 | 7.67 | 3.99 | |
| 5 | 1.10 | 7.32 | 3.41 | 7.40 | 3.32 |