Figure 3.

Motor deficits in rats with neonatal pyramidotomy. (A) Schematic of the intact CST that contributes to function of the unimpaired (left forepaw) and the impaired (right forepaw) forelimbs. (B) Pasta manipulation. The rats with neonatal pyramidotomy (Px) made fewer adjustments with their right forepaw than the control rats. No significant differences were detected in the amount of adjustments made by the left forepaw between the control and the Px rats. (C) Ladder walking. The right forepaw of the Px rats had a greater error rate percentage compared to that of the controls; however, left forepaw placement error was similar in the control and the Px rats. In addition, there were greater errors made with the right forepaw than the left forepaw in the Px rats. Data = mean ± SEM. Plotted dots represent each rat’s behavioral data points in each group. Each rat’s data are identified by the color of the dot. **p < 0.01.