Table 1.
Correlation between VCAM-1 and CCL18 expression and clinicopathologic characteristics of PDAC patients
| Characteristics | N of cases | VCAM-1 level | CCL18 level | ||||||
|---|---|---|---|---|---|---|---|---|---|
| L | M | H | p value | L | M | H | p value | ||
| Total cases | 134 | 33 | 42 | 59 | 28 | 55 | 51 | ||
| Gender | 0.619 | 0.990 | |||||||
| Male | 77 | 21 | 22 | 34 | 16 | 32 | 29 | ||
| Female | 57 | 12 | 20 | 25 | 12 | 23 | 22 | ||
| Age | 0.767 | 0.979 | |||||||
| <60 | 59 | 14 | 17 | 28 | 12 | 24 | 23 | ||
| ≥60 | 75 | 19 | 25 | 31 | 16 | 31 | 28 | ||
| Differentiation | 0.448 | 0.169 | |||||||
| Well | 22 | 4 | 5 | 13 | 1 | 9 | 12 | ||
| Moderate | 86 | 24 | 29 | 33 | 22 | 33 | 31 | ||
| Poor | 26 | 5 | 8 | 13 | 5 | 13 | 8 | ||
| TNM stage (AJCC)b | 0.009** | 0.036* | |||||||
| I | 35 | 16 | 10 | 9 | 12 | 15 | 8 | ||
| II | 36 | 7 | 15 | 14 | 9 | 16 | 11 | ||
| III | 41 | 7 | 9 | 25 | 4 | 18 | 19 | ||
| IV | 22 | 3 | 8 | 11 | 3 | 6 | 13 | ||
| Lymph node metastasis | 0.004** | 0.275 | |||||||
| Negative | 56 | 22 | 15 | 19 | 14 | 25 | 17 | ||
| Positive | 78 | 11 | 27 | 40 | 14 | 30 | 34 | ||
| Perineural invasion | 0.013* | 0.482 | |||||||
| Negative | 45 | 18 | 12 | 15 | 11 | 20 | 14 | ||
| Positive | 89 | 15 | 30 | 44 | 17 | 35 | 37 | ||
aχ2-test, *p < 0.05, **p < 0.01.
bAmerican Joint Committee on Cancer (AJCC), patients were staged in accordance with the 7th Edition of the AJCC Cancer’s’ TNM Classification; N of cases number of cases; T stage tumor stage; TNM tumor node metastasis; L low; M moderate; H high