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. 2018 Apr 18;8:6173. doi: 10.1038/s41598-018-24260-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Association between T2-signal and the diameter (A) and Knosp score (B) of somatotropinomas. The diameter of GH secreting adenomas was measured in millimetres. APD: anteroposterior diameter; TD: transverse diameter; CCD: craniocaudal diameter. Data represent median ± interquartile range. (C) Classification of T2-weighted signal of GH secreting pituitary adenomas: T2-hyperintense adenomas, upper-panel and T2-isointense adenomas, lower-panel. Tumour region was indicated with an arrow in coronal MRI (left), and in T2-weighted axial MRI (middle), the tumour area was indicated by a circle in right panel.