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. 2018 Apr 18;8:6173. doi: 10.1038/s41598-018-24260-y

Table 2.

Characteristics of pituitary adenomas based on Knosp score.

Knosp score 0 1 2 3 4 P value
% 17.6% 17.6% 23.5% 11.8% 29.4%
Age (years) 35.67 ± 7.51 29.33 ± 14.50 29.50 ± 13.03 62.00 ± 15.56 47.40 ± 18.68 0.116
IGF-1 (ng/mL) 547.80 ± 116.25 423.18 ± 264.93 516.47 ± 300.18 493.05 ± 311.95 597.91 ± 401.64 0.956
Nadir GH (ng/mL) 11.41 ± 11.80 10.95 ± 9.32 9.79 ± 10.46 8.84 ± 7.98 8.75 ± 10.08 0.861
Sex (♂/♀) 3/1 1/3 3/3 0/2 2/4 0.067
APD (mm) 10.00 ± 4.58 15.20 ± 4.70 18.70 ± 3.50 16.90 ± 1.56 26.50 ± 5.54 0.004
TD (mm) 8.77 ± 2.85 17.87 ± 3.01 18.15 ± 4.57 17.65 ± 3.32 27.12 ± 9.36 0.022
CCD (mm) 11.10 ± 4.76 15.17 ± 4.76 16.97 ± 5.98 17.90 ± 4.38 29.60 ± 6.42 0.003

APD: anteroposterior diameter; TD: transverse diameter; CCD: craniocaudal diameter.