Table 3.
Risk factors for patients with SS or RA to develop RA/SS.
| Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| Univariate HR (95% Cl) | P-value | Multivariate HR (95%Cl) | P-value | ||
| SS develop RA | Arthritis | 92.076 (21.325–397.553) | <0.001 | 44.804 (9.405–21.434) | <0.001 |
| ILD | 1.644 (0.844–3.203) | 0.144 | / | / | |
| Anaemia | 4.072 (2.244–7.389) | <0.001 | / | >0.05 | |
| RF | 10.532 (5.077–21.847) | <0.001 | 5.973 (2.228–16.016) | <0.001 | |
| Anti-CCP | 11.232 (5.750–1.941) | <0.001 | 2.545 (1.067–6.068) | 0.035 | |
| RA develop SS | Xerostomia | 11.591 (4.977–26.992) | <0.001 | 3.960 (1.110–14.122) | 0.034 |
| Xeophthalmia | 8.111 (3.473–18.944) | <0.001 | / | >0.05 | |
| ILD | 9.847 (4.089–24.713) | <0.001 | 6.210 (1.903–20.270) | 0.002 | |
| Leukocytopenia | 5.161 (0.649-41.041) | 0.121 | / | / | |
| Anti-SSA | 30.237 (8.681–105.321) | <0.001 | 24.640 (6.228–97.481) | <0.001 | |
SS: Sjogren syndrome; RA: Rheumatoid arthritis; OR: Odds ratio; CI: Confidence interval; ILD: Interstitial lung disease; RF: Rheumatoid factor.