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. 2018 Apr 18;8:6220. doi: 10.1038/s41598-018-24437-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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T cell subfractions in human HCC tumor tissue (HCC), adjacent tissue (TaT) and healthy liver. (HL). CIBERSORT immune cell fractions were determined for each patient; each dot represents one patient. Mean values and standard deviations for each cell subset including CD4 memory resting cells (A), CD8 cells (B), follicular helper (C), T cells gamma delta (D), CD4 memory activated (E) and Tregs (F) were calculated for each patient group and compared using one-way ANOVA. *p < 0.05; **p < 0.01.