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. 2018 Apr;103-105:36–46. doi: 10.1016/j.vph.2017.12.063

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© 2018 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 5 — Contractile responses to UDP-glucose and the selective P2Y₁₄ receptor agonist MRS2690 are attenuated by the selective P2Y₁₄ receptor antagonist PPTN. The effect of PPTN (1 μM) on contractile responses to UDP-glucose (a), MRS2690 (b), and UTP (c) in porcine coronary arteries in the presence of forskolin (0.1 μM) and U46619. Analysis of the curves showed that these were significantly different in the absence and presence of PPTN for UDP-glucose (P < 0.01) and MRS2690 (P < 0.001) (extra sum of squares F test). In contrast, there was no significant difference in the responses to UTP. Data are mean ± S.E.M.