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. Author manuscript; available in PMC: 2018 Apr 19.
Published in final edited form as: Am J Geriatr Psychiatry. 2017 Jan 4;25(7):683–693. doi: 10.1016/j.jagp.2016.12.017

Figure 2.

Figure 2

Results from Longitudinal Model. Apathy (NPI-Q apathy item scores) as predicted by the fixed effects predictors supramarginal FDG metabolism and diagnostic groups from the longitudinal model across time (in years). The fixed effects model shows a longitudinal positive association between hypometabolism and rate of progression of apathy over time. For purposes of the graph, other covariates in the model were set at the values: FDG metabolism in the posterior cingulate =1 (mean); sex = male; Antidepressant medication = yes (presence of antidepressant medication). Circles = AD dementia; squares = MCI; triangles = CN. Solid line = low FDG metabolism for the supramarginal gryus (1 standard deviation below the mean); Dashed line = high FDG metabolism for the supramarginal gryus (1 standard deviation above the mean). NPI-Q: Neuropsychiatric Inventory Questionnaire; FDG: 18F-fluorodeoxyglucose; AD: Alzheimer’s disease; MCI: mild cognitive impairment; CN: cognitively normal.