Table 2.
Comparison of RNA Integrity Number Values in Human Tissues
Tissue | RIN (average ± SD) | n | p |
---|---|---|---|
Cerebellum | 8.3 ± 0.6 | 15 | n/a |
Prefrontal cortex | 7.8 ± 0.5 | 15 | 0.34 |
Psoas muscle | 7.2 ± 0.9 | 15 | 0.009 |
Heart | 7.1 ± 0.7 | 15 | 0.003 |
Testis | 7.2 ± 0.8 | 15 | 0.007 |
Liver | 5.4 ± 1.3 | 15 | <0.001 |
Lung | 5.4 ± 1.6 | 15 | <0.001 |
Kidney | 4.4 ± 1.5 | 15 | <0.001 |
Ileum | 2.6 ± 0.2 | 5 | <0.001 |
Spleen | 2.1 ± 0.2 | 5 | <0.001 |
RIN values were determined on RNA isolated from brain and systemic tissue from a group of 15 donors. Only five cases included ileum and spleen in addition to the other tissues. The p-values apply to the difference in RIN values between the cited tissue and cerebellum.
SD, standard deviation.