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. 2018 May;188(5):1246–1262. doi: 10.1016/j.ajpath.2018.01.008

Figure 3.

Figure 3

Residual blood perfusion and tissue oxygenation are similar in the ischemic limbs of C57 and B/c mice after 6 hours of acute hind limb ischemia. A: Representative laser Doppler perfusion images (LDPIs) of the ischemic left [Isch. (L)] and control right [Ctrl. (R)] limbs in the supine position after 6 hours of acute hind limb ischemia. B: Representative LDPIs of the Isch. (L) and Ctrl. (R) limbs in the prone position after 6 hours of acute hind limb ischemia. C and D: Quantification of flux measurements in the supine position represented as arbitrary perfusion units (AU) and as ratio of the Isch. (L)/Ctrl. (R) limbs. E and F: Quantification of flux measurements in the prone position represented as AUs and as a ratio of the Isch. (L)/Ctrl. (R) limbs. G and H: Laser Doppler flowmetry (LDF) measurements made directly over the lateral head of the gastrocnemius muscles in the absence of interference from skin pigmentation. I: Percentage oxygen saturation values measured directly over the vastus lateralis, lateral head of the gastrocnemius, tibialis anterior, and plantar paw in the Ctrl. (R) and Isch. (L) limbs of both strains. Bars indicate median, interquartile range, and maximum/minimum values (D, F, and H). Data are expressed as means ± SEM (C, E, G, and I). n = 7 BALB/c (C and D); n = 8 C57BL/6 (C and D); n = 14 per group (E and F); n = 18 per group (G and H); n = 14 per group (I). ∗P < 0.05.