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(A) In-cell immunofluorescence assay of biomarkers (target proteins) in 3D cell culture on the microarray chip [34, 64]. (B) Micropillar/microwell chip platform for RNAi delivery into 3D cell culture [64]. The micropillar chip can be transferred to a microwell chip containing a target compound after incubation with lentiviruses carrying the RNAi library.
