Table 1.

Experimental condition about dose‐dependent regulation of enhancement of hyperactivation by progesterone and 17β‐estradiol as shown in Fig. 2

	Concentration of steroids
	Progesterone (P) (ng/mL)	17β‐Estradiol (E)
Experiment 1 (Fig. 2a, b)
Vehicle	–	–
10 ng/mL P	10	–
P + 1 pg/mL E	10	1 pg/mL
P + 10 pg/mL E	10	10 pg/mL
P + 100 pg/mL E	10	100 pg/mL
P + 1 ng/mL E	10	1 ng/mL
P + 10 ng/mL E	10	10 ng/mL
Experiment 2 (Fig. 2c, d)
Vehicle	–	–
20 ng/mL P	20	–
P + 2 pg/mL E	20	2 pg/mL
P + 20 pg/mL E	20	20 pg/mL
P + 200 pg/mL E	20	200 pg/mL
P + 2 ng/mL E	20	2 ng/mL
P + 20 ng/mL E	20	20 ng/mL
Experiment 3 (Fig. 2e, f)
Vehicle	–	–
40 ng/mL P	40	–
P + 4 pg/mL E	40	4 pg/mL
P + 40 pg/mL E	40	40 pg/mL
P + 400 pg/mL E	40	400 pg/mL
P + 4 ng/mL E	40	4 ng/mL
P + 40 ng/mL E	40	40 ng/mL