Table 2.
Experimental conditions for dose‐dependent regulation of enhancement of hyperactivation by progeteone, 17β‐estradiol and diethylstilbestrol as shown in Figs. 6 and 7
| Concentration of steroids | |||
|---|---|---|---|
| Progesterone (P) (ng/mL) | 17β‐Estradiol (E) (pg/mL) | Diethylstilbestrol (DES) (pg/mL) | |
| Experiment 1 (Fig. 6a, b) | |||
| Vehicle | – | – | – |
| 20 ng/mL P | 20 | – | – |
| P + E (2 pg/mL) | 20 | 2 | – |
| P + DES (2 pg/mL) | 20 | – | 2 |
| P + mixture of E and DES | 20 | 2 | 2 |
| Experiment 2 (Fig. 6c, d) | |||
| Vehicle | – | – | – |
| 20 ng/mL P | 20 | – | – |
| P + E (20 pg/mL) | 20 | 20 | – |
| P + DES (2 pg/mL) | 20 | – | 2 |
| P + mixture of E and DES | 20 | 20 | 2 |
| Experiment 3 (Fig. 6e, f) | |||
| Vehicle | – | – | – |
| 20 ng/mL P | 20 | – | – |
| P + E (20 pg/mL) | 20 | 20 | – |
| P + DES (20 pg/mL) | 20 | – | 20 |
| P + mixture of E and DES | 20 | 20 | 20 |
| Experiment 4 (Fig. 7) | |||
| Vehicle | – | – | – |
| 20 ng/mL P | 40 | – | – |
| P + E (4 pg/mL) | 40 | 4 | – |
| P + DES (4 pg/mL) | 40 | – | 4 |
| P + mixture of E and DES | 40 | 4 | 4 |