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Table 1.

Comparison of medical care costs between singleton, twin, triplet, and quadruplet pregnancies

Control group High‐order multiple group Comparison using anova P‐value
Singleton (n = 58) Twin (n = 21) Triplet (n = 14) Quadruplet (n = 1)
Gestational age at delivery (weeks)  39.4 ± 1.7  35.6 ± 4.1  31.9 ± 2.6     25.1 <0.001
Length of maternal hospital stay (days)  18.3 ± 21.5  46.1 ± 33.8 102.2 ± 33.2    108 <0.001
Maternal costs (× 1000 yen)  530 ± 467  1124 ± 709  2070 ± 525   3522 <0.001
Birthweight (g) 2886 ± 425  2117 ± 623  1430 ± 373    633 ± 77 <0.001
Length of neonatal hospital stay (days)   9.0 ± 4.6  30.9 ± 38.1  52.9 ± 29.9    133 <0.001
Cost per neonate (× 1000 yen)  173 ± 410 1889 ± 3061  3247 ± 2350 10 360 ± 85 <0.001
Total family cost (× 1000 yen)  703 ± 680 4903 ± 6199 11810 ± 4869 44 961 <0.001