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. 2018 Apr 11;12(Suppl 1):10. doi: 10.1186/s12918-018-0529-2

Table 11.

List of model equations used in mitochondrial Ca2+ handling (obtained from [10])

Equation Biological significance
Mitochondrial uniporter equations
MWCnum=(CAC/6)∗((1+(CAC/6))3) MWC numerator
MWCdenom=((1+(CAC/6))4)+(50/((1+(CAC/0.38))2.8)) MWC denominator
MWC=MWCnum/MWCdenom MWC fraction value
VuniD=PSI91/13.35 Uniporter potential exponent
Juni=ρuniVuniDMWCCAMexpVuniD/1expVuniD1PTPh Rate of transport through uniporter considering PTP in high conductance state
Na+/Ca2+ exchanger equations
VncD=expPSI91/53.4 Na+/Ca2+ exchanger potential generated
Jnc=ρncVncD1/1+9.4/3021/1+0.003Dmito/CAM1PTPh Rate of Na+/Ca2+ exchange