Table 5.

List of initial conditions [7–9]

Parameters	Value	Biological significance
PSI(0)	164 mV	Base potential at time 0
CAM(0)	0.05 μM	Mitochondrial Ca2+ concentration at time 0
CAC(0)	0.05 μM	Cytosolic Ca2+ concentration at time 0
CAER(0)	11 μM	ER Ca2+ concentration at time 0
ADPm(0)	4.46 mM	Mitochondrial ADP concentration at time 0
ADPi(0)	0.028 mM	Cytosolic ADP concentration at time 0
NADHm(0)	0.16 mM	Mitochondrial NADH concentration at time 0
h(0)	95%	Percentage of closed channels at time 0
a(0)	0 mM	β-amyloid concentration at time 0
y(0)	0	Secondary slow process involved in PTP opening at time 0
PTPh(0)	0	PTP closed at time 0
PTPl(0)	0	PTP closed at time 0