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. 2018 Apr 18;18:441. doi: 10.1186/s12885-018-4358-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Metastatic lesion formation. Among NSCLC, H1299, a metastatic p53 mutant cell formed significantly more metastatic lesions as compared to A549 cells (a; b vs d) per high power field (HPF). H460 cells also formed metastatic lesions (a and c). Among SCLC cell lines, H69 formed more metastatic lesions than H446 and SHP-77 (e–h). In breast cancer cells, MDAMB231, a triple negative cell line, formed significantly more metastatic lesions than MCF-7 cells (i–k)