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. 2018 Apr 19;6:72. doi: 10.1186/s40168-018-0450-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — a Prevalence changes for three taxa showing statistically significant effects (p < 0.05 after multiple hypothesis testing). b Predictability of diet based on fecal samples at the end of the study. Receiver operating curves for diet classification (estimated by leave-one-out cross-validation). mOTUs refer to metagenomics OTUs [66]. c CAZy enzyme classes which show a differential response to the diet change (HPLC vs. LPHC). Shown is the ratio between pre-intervention and post-intervention samples (subjects where both samples were below the detection limit were removed from the analysis) (*p < 0.05, **p < 0.01, ***p < 0.001; Gehan’s two-sided test after multiple hypothesis correction)