Skip to main content
. Author manuscript; available in PMC: 2018 Apr 19.
Published in final edited form as: Biochemistry. 2017 Nov 10;56(47):6200–6210. doi: 10.1021/acs.biochem.7b00741

Table 1. Effects of single nucleotide substitutions on Zta binding a non-cytosine containing version of the TRE motif, TGAGTAAT.

Shown are Z-scores for Zta binding containing the indicated nucleotides at each position. Z-scores for nucleotides that do not change the motif are in bold. 5mCG Z-scores are shown for substitutions giving rise to a CG dinucleotide.

TGAGTAAT −4 −3 −2 0 2 3 4
T G A G T A A
A 9 11 162 2 13 162 162
C 10 14 16 46 116 145 5
G 7 162 9 162 3 26 8
T 162 36 67 4 162 12 20
M 82 7 21 7 187 51 6
H 66 6 4 3 174 13 7
5mCG 43 - 7 - - - -